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Search Results for " hepatitis b "

20

Compounds

Cat No. Product Name Synonyms Targets
TP2231 HBcAg [Hepatitis B virus] (18-27) Others
HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person.
TP1520 Hepatitis B Virus Core (128-140) Hepatitis B Virus Core 128-140
The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during t...
T23407 Surface antigen (208-215) [Hepatitis B Virus] Others
The nucleocapsid of the hepatitis B virus is covered by an envelope of HBV surface antigen (HBsAg), which has the common, group-specific determinant a. The four major subtypes of HBsAg, adw, adr, ayw and ayr, are generat...
TN1482 Chamaechromone P450 , HBV
Chamaechromone is a natural product isolated from the roots of Stellera chamaejasme L.. Chamaechromone has anti-HBV and insecticidal activity.
T4S1718 Punicalin HBV , HIV Protease
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM).
T11669 IR415 HBV
IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 i...
T3273 Bifendate Bifendatatum HBV , Reverse Transcriptase
Bifendate (Bifendatatum) is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.
T5832 Besifovir HBV
Besifovir, a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV).
T27527 HBF-0259 HBF 0259 Antiviral
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV...
T16366 NVR 3-778 HBV
NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.
T1922 Pseudolaric Acid B Apoptosis , p38 MAPK , Ferroptosis , HBV , Autophagy , Antifungal
Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.
T20048 Vidarabine phosphate Antiviral
Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.
T2780 Catalpol Catalpinoside,Digitalis purpurea L Others , HBV
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.
T4475 JNJ-632 HBV
JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.
T3S0872 Paederoside Antiviral , HBV
1. Paederoside is a potent deterrent against the beetle was isolated from the aphid . 2. Paederoside displays high anti-tumor promoting activity against the Epstein-Barr virus activation.
T11409 GLP-26 HBV
GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM...
TQ0017 AB-423 HBV
AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).
T3810 Saikosaponin B2 Others , HCV Protease
Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with...
T3449 Bay 41-4109 racemate HBV
BAY 41-4109 racemate is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
T6846 Vesatolimod GS-9620 Apoptosis , HCV Protease , HBV , TLR , HIV Protease
Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.
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TargetMol